A Stochastic Petri Net-Based Model of the Involvement of Interleukin 18 in Atherosclerosis

Interleukin 18 (IL-18) is a proinflammatory and proatherogenic cytokine with pleiotropic properties, which is involved in T and NK cell maturation and the synthesis of other inflammatory cytokines and cell adhesion molecules. It plays a significant role in orchestrating the cytokine cascade, accelerates atherosclerosis and influences plaque vulnerability. To investigate the influence of IL-18 cytokine on atherosclerosis development, a stochastic Petri net model was built and then analyzed. First, MCT-sets and t-clusters were generated, then knockout and simulation-based analysis was conducted. The application of systems approach that was used in this research enabled an in-depth analysis of the studied phenomenon. Our results gave us better insight into the studied phenomenon and allow revealing that activation of macrophages by the classical pathway and IL-18-MyD88 signaling axis is crucial for the modeled process.     

Nb和时效时间对热轧中锰TRIP钢中P偏聚的影响

热轧态中锰TRIP钢首先经650 ℃退火2 h,随后在550 ℃进行等温时效热处理,采用场发射扫描电镜(FE-SEM)研究该钢中P的偏聚和时效析出行为的变化情况。结果表明,中锰TRIP钢中P在晶界的偏聚是一种非平衡偏聚现象,临界时间约为50 h,与理论计算结果48 h较为吻合。在局部偏聚区域内,C与P存在共偏聚的关系,即P偏聚量高的地方,C含量也高。而合金元素Nb具有抑制P偏聚的效果,在20~70 h时效时间内,可以相对降低6.57%~19.5%的最大P偏聚量。根据电子背散射衍射(EBSD)菊池线分析,P偏聚量低于2.28at%时,P为固溶状态,高于2.28at.%时,P为析出状态。     

夹杂物对工程机械用钢Q345FCA疲劳寿命的影响

采用QBWP-6000J型简支梁旋转弯曲疲劳试验机测定了高疲劳寿命工程机械用钢Q345FCA的疲劳寿命;采用扫描电镜(SEM)对疲劳断口形貌进行了观察,并用附带的能谱仪(EDS)寻找断口上的夹杂物;借助夹杂物自动分析系统对钢中的夹杂物进行了分析。通过对试验数据的分析,计算得出了Q345FCA钢和Q345钢夹杂物的表面临界尺寸、次表面临界尺寸和内部临界尺寸。结果表明,Q345FCA钢的疲劳极限为273 MPa,Q345钢的疲劳极限为266 MPa。Q345FCA钢和Q345钢中夹杂物尺寸均小于临界夹杂物尺寸,且断口形貌显示所有疲劳断裂均不是由夹杂物所引起,夹杂物不是疲劳源。     

一种下肢运动意图识别算法性能实时测评系统* .txt

摘要：对腿部运动意图识别算法的实时性能进行综合可靠的评价是实现下肢假肢灵活稳定控制的前提。提出一种逐层分级的基于下肢运动意图识别算法的实时测评方法，对算法的可靠性、稳定性以及运动意图识别速度进行综合评价。利用开发的运动意图识别算法评测系统，对基于肌电信号源和机械信号源的两种运动意图识别算法进行了实时性能测试，发现肌电信号源的算法识别时间大于机械信号源算法，但是其算法稳定性优于机械信号源算法。进一步地，还利用该评测系统有效地区分出正常识别策略与异常识别策略，发现正常策略的动作识别稳定系数比异常策略高25%左右。因此，所提的基于下肢运动意图识别算法的实时测评方法，能够对不同信号源算法以及不同识别策略的实时性能进行有效评价，为智能下肢假肢控制系统开发提供可供参考的测试平台。 .txt     

基于机器视觉的运煤车车号识别技术研究

在铁路运煤装车过程中为了快速、准确地识别车号,提出一种基于机器视觉的运煤车车号识别技术。将连通区域提取与投影分割法结合,实现车号的粗定位、细分割,并对图像中的断裂字符进行二次分割,构建了基于BP神经网络的分类模型进行车号识别,提升了煤炭装车的效率和精度。     

New insight to the oxidation kinetics of silicon-containing steel at high temperature

This study investigated the oxidation kinetics of silicon-containing steel at 1150–1300 °C using a Simultaneous Thermal Analyzer under atmospheric conditions similar to that of an industry reheating furnace. There is a critical time point for the oxidation kinetics at an oxygen concentration of 4·0 vol.-%., following which the oxidation rate constant increases with the increasing oxidation temperature. The model coefficient A in the kinetic oxidation equation was found to be constant. However, before the critical time point, the oxidation rate constant remained unchanged; the model coefficient A decreased with the increasing temperature. Therefore, the kinetic model of silicon-containing steel for isothermal oxidation was observed to be a modified one on the basis of the experimental data. In addition, the critical time point was prolonged with the increasing isothermal oxidation temperature. Moreover, the oxidation activation energy of the tested silicon-containing steel was 366·16 kJ mol^?1.     

Empirical surveys of frontier applications: a meta‐review

This contribution is the first attempt to systematically review all empirical surveys that so far have been made available in the broad field of efficiency and productivity analysis using frontier estimation methodologies. We provide a systematic bibliometric review on the many empirical surveys in the field of efficiency and productivity analysis, the most relevant concepts, areas, overlaps, and potentials to explore from its introduction to the most recent surveys. We combine the United Nations’ International Standard Industrial Classification (ISIC) taxonomy for the economic activity with the Journal of Economic Literature (JEL) classification system to classify the empirical surveys and to identify the current gaps in the literature. In addition to the most relevant/generic potential areas for applications (according to the United Nation's ISIC), this methodology provides a cluster analysis with the most relevant concepts that have been considered so far (according to the JEL codes). This overview brings an interesting guide for future work to develop the whole field.     

神经网络全局势函数在多相催化中的应用

当今的多相催化研究需要新的技术和方法从原子尺度上表征活性中心结构和反应中间体。本文作者课题组近期开发了理论模拟新技术来探索催化剂活性位点结构，即基于神经网络势函数的大规模原子模拟（LASP）软件中实现的全局神经网络势函数计算方法。本文介绍了该方法可以显著降低催化体系的计算代价，而维持与密度泛函理论同一级别的计算精度，从而解决多相催化中的许多复杂问题。本文对神经网络势函数方法的实现细节和目前已实现的应用场景进行了详细介绍。神经网络势函数可以用来预测材料晶体结构，理解高压氢化条件下TiO₂表面的结构演化和确定三元氧化物ZnCrO晶相中合成气制甲醇活性位点。最后文章分析了神经网络势函数的局限性和今后可能的三个研究方向，即材料性质预测、多元素体系神经网络势函数构造和化学反应拟合。     

命名实体识别技术综述

命名实体识别是自然语言处理中的热点研究方向之一,目的是识别文本中的命名实体并将其归纳到相应的实体类型中。首先阐述了命名实体识别任务的定义、目标和意义,分析提出了命名实体识别的主要难点在于领域命名实体识别局限性、命名实体表述多样性和歧义性、命名实体的复杂性和开放性;然后介绍了命名实体识别研究的发展进程,从最初的规则和字典方法到传统的统计学习方法再到现在的深度学习方法,不断地将新技术应用到命名实体识别研究中以提高性能;接着系统梳理了当下命名实体识别任务中的若干热门研究点,分别是匮乏资源下的命名实体识别、细粒度命名实体识别、嵌套命名实体识别以及命名实体链接;最后针对评判命名实体识别模型的好坏,总结了常用的若干数据集和实验测评指标,并给出了未来的研究建议。     

Manpower supply planning for aircraft line maintenance under stochastic incidents

We plan the manpower supply for aircraft line maintenance, taking into account two types of stochastic incidents: manpower demands for a flight and the number of aircraft needing to be serviced at one time. The problem is solved to find the shift and maintenance group combinations best suited for the given airline. The optimal aircraft maintenance certification for a crew is also analyzed to improve the entire manpower structure. In addition, the addition of temporary manpower required for actual daily operations is also considered as a part of understanding the total manpower utilized in actual operations. An integrated method including scenario generation and a stochastic model is developed to deal with the problem. Finally, we perform a case study based on operating data obtained from a major airline in Taiwan. The results and findings are compared with the airline’s current manpower plan in the discussion, and suggestions for improvement are made.